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Selective Transmission of R5 HIV-1 over X4 HIV-1 at the Dendritic Cell–T Cell Infectious Synapse Is Determined by the T Cell Activation State

Dendritic cells (DCs) are essential antigen-presenting cells for the induction of T cell immunity against HIV. On the other hand, due to the susceptibility of DCs to HIV infection, virus replication is strongly enhanced in DC–T cell interaction via an immunological synapse formed during the antigen...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takuya, Tsunetsugu-Yokota, Yasuko, Mitsuki, Yu-ya, Mizukoshi, Fuminori, Tsuchiya, Takatsugu, Terahara, Kazutaka, Inagaki, Yoshio, Yamamoto, Naoki, Kobayashi, Kazuo, Inoue, Jun-ichiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627922/
https://www.ncbi.nlm.nih.gov/pubmed/19180188
http://dx.doi.org/10.1371/journal.ppat.1000279