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Loss of Magel2, a Candidate Gene for Features of Prader-Willi Syndrome, Impairs Reproductive Function in Mice

BACKGROUND: MAGEL2 is one of several genes typically inactivated in the developmental obesity disorder Prader-Willi syndrome (PWS). The physiological consequences of loss of MAGEL2, but without the concurrent loss of other PWS genes, are not well understood. Gene-targeted mutation of Magel2 in mice...

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Detalles Bibliográficos
Autores principales: Mercer, Rebecca E., Wevrick, Rachel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627930/
https://www.ncbi.nlm.nih.gov/pubmed/19172181
http://dx.doi.org/10.1371/journal.pone.0004291