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Derangement of a Factor Upstream of RARα Triggers the Repression of a Pleiotropic Epigenetic Network
BACKGROUND: Chromatin adapts and responds to extrinsic and intrinsic cues. We hypothesize that inheritable aberrant chromatin states in cancer and aging are caused by genetic/environmental factors. In previous studies we demonstrated that either genetic mutations, or loss, of retinoic acid receptor...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627936/ https://www.ncbi.nlm.nih.gov/pubmed/19173001 http://dx.doi.org/10.1371/journal.pone.0004305 |