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Short Telomeres Initiate Telomere Recombination in Primary and Tumor Cells
Human tumors that lack telomerase maintain telomeres by alternative lengthening mechanisms. Tumors can also form in telomerase-deficient mice; however, the genetic mechanism responsible for tumor growth without telomerase is unknown. In yeast, several different recombination pathways maintain telome...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627939/ https://www.ncbi.nlm.nih.gov/pubmed/19180191 http://dx.doi.org/10.1371/journal.pgen.1000357 |