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Antiallodynic Effect of Pregabalin in Rat Models of Sympathetically Maintained and Sympathetic Independent Neuropathic Pain
Pregabalin binds to the voltage-dependent calcium channel α2δ subunit and modulates the release of neurotransmitters, resulting in analgesic effects on neuropathic pain. Neuropathic pain has both sympathetically maintained pain (SMP) and sympathetic independent pain (SIP) components. We studied the...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628009/ https://www.ncbi.nlm.nih.gov/pubmed/17326244 http://dx.doi.org/10.3349/ymj.2007.48.1.41 |