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A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics

BACKGROUND: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differences in gel migration and sample variability make efficient spot alignment very difficult to obtain, and, as consequence...

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Detalles Bibliográficos
Autores principales: Pérès, Sabine, Molina, Laurence, Salvetat, Nicolas, Granier, Claude, Molina, Franck
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628390/
https://www.ncbi.nlm.nih.gov/pubmed/18957120
http://dx.doi.org/10.1186/1471-2105-9-460