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A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
BACKGROUND: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differences in gel migration and sample variability make efficient spot alignment very difficult to obtain, and, as consequence...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628390/ https://www.ncbi.nlm.nih.gov/pubmed/18957120 http://dx.doi.org/10.1186/1471-2105-9-460 |