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A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection

The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is what role(s) this feedback plays in our ability to he...

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Detalles Bibliográficos
Autores principales: Taranda, Julian, Maison, Stéphane F, Ballestero, Jimena A, Katz, Eleonora, Savino, Jessica, Vetter, Douglas E, Boulter, Jim, Liberman, M. Charles, Fuchs, Paul A, Elgoyhen, A. Belén
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628405/
https://www.ncbi.nlm.nih.gov/pubmed/19166271
http://dx.doi.org/10.1371/journal.pbio.1000018