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A Novel Function for Fragile X Mental Retardation Protein in Translational Activation

Fragile X syndrome, the most frequent form of inherited mental retardation, is due to the absence of Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein involved in several steps of RNA metabolism. To date, two RNA motifs have been found to mediate FMRP/RNA interaction, the G-quartet...

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Detalles Bibliográficos
Autores principales: Bechara, Elias G, Didiot, Marie Cecile, Melko, Mireille, Davidovic, Laetitia, Bensaid, Mounia, Martin, Patrick, Castets, Marie, Pognonec, Philippe, Khandjian, Edouard W, Moine, Hervé, Bardoni, Barbara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628407/
https://www.ncbi.nlm.nih.gov/pubmed/19166269
http://dx.doi.org/10.1371/journal.pbio.1000016