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A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles

We discovered a new small non-coding RNA (sRNA) gene, vrrA of Vibrio cholerae O1 strain A1552. A vrrA mutant overproduces OmpA porin, and we demonstrate that the 140 nt VrrA RNA represses ompA translation by base-pairing with the 5′ region of the mRNA. The RNA chaperone Hfq is not stringently requir...

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Detalles Bibliográficos
Autores principales: Song, Tianyan, Mika, Franziska, Lindmark, Barbro, Liu, Zhi, Schild, Stefan, Bishop, Anne, Zhu, Jun, Camilli, Andrew, Johansson, Jörgen, Vogel, Jörg, Wai, Sun Nyunt
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628432/
https://www.ncbi.nlm.nih.gov/pubmed/18681937
http://dx.doi.org/10.1111/j.1365-2958.2008.06392.x