Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice

OBJECTIVE—Imatinib has been reported to induce regression of type 2 diabetes in chronic leukemia patients. However, the mechanism of diabetes amelioration by imatinib is unknown, and it is uncertain whether imatinib has effects on type 2 diabetes itself without other confounding diseases like leukem...

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Detalles Bibliográficos
Autores principales: Han, Myoung Sook, Chung, Kun Wook, Cheon, Hyae Gyeong, Rhee, Sang Dal, Yoon, Chang-Hwan, Lee, Moon-Kyu, Kim, Kwang-Won, Lee, Myung-Shik
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628605/
https://www.ncbi.nlm.nih.gov/pubmed/19171749
http://dx.doi.org/10.2337/db08-0080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628605/
https://www.ncbi.nlm.nih.gov/pubmed/19171749
http://dx.doi.org/10.2337/db08-0080

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