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Enhanced Expression of Janus Kinase–Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

OBJECTIVE—Glomerular mesangial expansion and podocyte loss are important early features of diabetic nephropathy, whereas tubulointerstitial injury and fibrosis are critical for progression of diabetic nephropathy to kidney failure. Therefore, we analyzed the expression of genes in glomeruli and tubu...

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Detalles Bibliográficos
Autores principales: Berthier, Celine C., Zhang, Hongyu, Schin, MaryLee, Henger, Anna, Nelson, Robert G., Yee, Berne, Boucherot, Anissa, Neusser, Matthias A., Cohen, Clemens D., Carter-Su, Christin, Argetsinger, Lawrence S., Rastaldi, Maria P., Brosius, Frank C., Kretzler, Matthias
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628622/
https://www.ncbi.nlm.nih.gov/pubmed/19017763
http://dx.doi.org/10.2337/db08-1328