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Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

OBJECTIVE—This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes association and considered the implications for the etiological heterogeneity of type 2 diabetes. RESEARCH DESIGN AND METHODS—We reanalyzed data fro...

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Detalles Bibliográficos
Autores principales: Timpson, Nicholas J., Lindgren, Cecilia M., Weedon, Michael N., Randall, Joshua, Ouwehand, Willem H., Strachan, David P., Rayner, N. William, Walker, Mark, Hitman, Graham A., Doney, Alex S.F., Palmer, Colin N.A., Morris, Andrew D., Hattersley, Andrew T., Zeggini, Eleftheria, Frayling, Timothy M., McCarthy, Mark I.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628627/
https://www.ncbi.nlm.nih.gov/pubmed/19056611
http://dx.doi.org/10.2337/db08-0906