Complex nature of SNP genotype effects on gene expression in primary human leucocytes

BACKGROUND: Genome wide association studies have been hugely successful in identifying disease risk variants, yet most variants do not lead to coding changes and how variants influence biological function is usually unknown. METHODS: We correlated gene expression and genetic variation in untouched p...

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Detalles Bibliográficos
Autores principales: Heap, Graham A, Trynka, Gosia, Jansen, Ritsert C, Bruinenberg, Marcel, Swertz, Morris A, Dinesen, Lotte C, Hunt, Karen A, Wijmenga, Cisca, vanHeel, David A, Franke, Lude
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628677/
https://www.ncbi.nlm.nih.gov/pubmed/19128478
http://dx.doi.org/10.1186/1755-8794-2-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628677/
https://www.ncbi.nlm.nih.gov/pubmed/19128478
http://dx.doi.org/10.1186/1755-8794-2-1

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