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Split-Cre Complementation Indicates Coincident Activity of Different Genes In Vivo

Cre/LoxP recombination is the gold standard for conditional gene regulation in mice in vivo. However, promoters driving the expression of Cre recombinase are often active in a wide range of cell types and therefore unsuited to target more specific subsets of cells. To overcome this limitation, we de...

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Detalles Bibliográficos
Autores principales: Hirrlinger, Johannes, Scheller, Anja, Hirrlinger, Petra G., Kellert, Beate, Tang, Wannan, Wehr, Michael C., Goebbels, Sandra, Reichenbach, Andreas, Sprengel, Rolf, Rossner, Moritz J., Kirchhoff, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628726/
https://www.ncbi.nlm.nih.gov/pubmed/19172189
http://dx.doi.org/10.1371/journal.pone.0004286