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Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

The oxidative stress theory of aging postulates that aging results from the accumulation of molecular damage caused by reactive oxygen species (ROS) generated during normal metabolism. Superoxide dismutases (SODs) counteract this process by detoxifying superoxide. It has previously been shown that e...

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Detalles Bibliográficos
Autores principales: Van Raamsdonk, Jeremy M., Hekimi, Siegfried
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628729/
https://www.ncbi.nlm.nih.gov/pubmed/19197346
http://dx.doi.org/10.1371/journal.pgen.1000361