Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells

BACKGROUND: Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound oxaliplatin has been extensively used in the treatment o...

Descripción completa

Detalles Bibliográficos
Autores principales: Leelawat, Kawin, Narong, Siriluck, Udomchaiprasertkul, Wandee, Leelawat, Surang, Tungpradubkul, Sumalee
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628866/
https://www.ncbi.nlm.nih.gov/pubmed/19128511
http://dx.doi.org/10.1186/1475-2867-9-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628866/
https://www.ncbi.nlm.nih.gov/pubmed/19128511
http://dx.doi.org/10.1186/1475-2867-9-3

Ejemplares similares