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Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells
BACKGROUND: Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound oxaliplatin has been extensively used in the treatment o...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628866/ https://www.ncbi.nlm.nih.gov/pubmed/19128511 http://dx.doi.org/10.1186/1475-2867-9-3 |