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Thermodynamic scaling behavior in genechips

BACKGROUND: Affymetrix Genechips are characterized by probe pairs, a perfect match (PM) and a mismatch (MM) probe differing by a single nucleotide. Most of the data preprocessing algorithms neglect MM signals, as it was shown that MMs cannot be used as estimators of the non-specific hybridization as...

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Detalles Bibliográficos
Autores principales: Ferrantini, Alessandro, Allemeersch, Joke, Van Hummelen, Paul, Carlon, Enrico
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628882/
https://www.ncbi.nlm.nih.gov/pubmed/19123958
http://dx.doi.org/10.1186/1471-2105-10-3