Pitfalls of the most commonly used models of context dependent substitution

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BACKGROUND: Neighboring nucleotides exert a striking influence on mutation, with the hypermutability of CpG dinucleotides in many genomes being an exemplar. Among the approaches employed to measure the relative importance of sequence neighbors on molecular evolution have been continuous-time Markov...

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Detalles Bibliográficos
Autores principales: Lindsay, Helen, Yap, Von Bing, Ying, Hua, Huttley, Gavin A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628887/
https://www.ncbi.nlm.nih.gov/pubmed/19087239
http://dx.doi.org/10.1186/1745-6150-3-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628887/
https://www.ncbi.nlm.nih.gov/pubmed/19087239
http://dx.doi.org/10.1186/1745-6150-3-52

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