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Pitfalls of the most commonly used models of context dependent substitution
BACKGROUND: Neighboring nucleotides exert a striking influence on mutation, with the hypermutability of CpG dinucleotides in many genomes being an exemplar. Among the approaches employed to measure the relative importance of sequence neighbors on molecular evolution have been continuous-time Markov...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628887/ https://www.ncbi.nlm.nih.gov/pubmed/19087239 http://dx.doi.org/10.1186/1745-6150-3-52 |