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Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells
BACKGROUND: The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β(3 )integrin inhibitors antagonize fibrinogen binding to α(IIb)β(3 )integrins on platelets and ligand binding to α(v)β(3 )integrins on vascular ce...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628888/ https://www.ncbi.nlm.nih.gov/pubmed/19108709 http://dx.doi.org/10.1186/1475-2840-7-36 |