A class frequency mixture model that adjusts for site-specific amino acid frequencies and improves inference of protein phylogeny

BACKGROUND: Widely used substitution models for proteins, such as the Jones-Taylor-Thornton (JTT) or Whelan and Goldman (WAG) models, are based on empirical amino acid interchange matrices estimated from databases of protein alignments that incorporate the average amino acid frequencies of the data...

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Detalles Bibliográficos
Autores principales: Wang, Huai-Chun, Li, Karen, Susko, Edward, Roger, Andrew J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628903/
https://www.ncbi.nlm.nih.gov/pubmed/19087270
http://dx.doi.org/10.1186/1471-2148-8-331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628903/
https://www.ncbi.nlm.nih.gov/pubmed/19087270
http://dx.doi.org/10.1186/1471-2148-8-331

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