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Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks

BACKGROUND: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications, changes in chromatin structure and patterns of DNA methylation across entire genomes. In these experiments, chromatin i...

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Detalles Bibliográficos
Autores principales: Nix, David A, Courdy, Samir J, Boucher, Kenneth M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628906/
https://www.ncbi.nlm.nih.gov/pubmed/19061503
http://dx.doi.org/10.1186/1471-2105-9-523