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Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
BACKGROUND: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications, changes in chromatin structure and patterns of DNA methylation across entire genomes. In these experiments, chromatin i...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628906/ https://www.ncbi.nlm.nih.gov/pubmed/19061503 http://dx.doi.org/10.1186/1471-2105-9-523 |