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An RIG-I-Like RNA Helicase Mediates Antiviral RNAi Downstream of Viral siRNA Biogenesis in Caenorhabditis elegans

Dicer ribonucleases of plants and invertebrate animals including Caenorhabditis elegans recognize and process a viral RNA trigger into virus-derived small interfering RNAs (siRNAs) to guide specific viral immunity by Argonaute-dependent RNA interference (RNAi). C. elegans also encodes three Dicer-re...

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Detalles Bibliográficos
Autores principales: Lu, Rui, Yigit, Erbay, Li, Wan-Xiang, Ding, Shou-Wei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629121/
https://www.ncbi.nlm.nih.gov/pubmed/19197349
http://dx.doi.org/10.1371/journal.ppat.1000286