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Predicting Peptide Structures in Native Proteins from Physical Simulations of Fragments
It has long been proposed that much of the information encoding how a protein folds is contained locally in the peptide chain. Here we present a large-scale simulation study designed to examine the extent to which conformations of peptide fragments in water predict native conformations in proteins....
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629132/ https://www.ncbi.nlm.nih.gov/pubmed/19197352 http://dx.doi.org/10.1371/journal.pcbi.1000281 |