Cargando…

Predicting Peptide Structures in Native Proteins from Physical Simulations of Fragments

It has long been proposed that much of the information encoding how a protein folds is contained locally in the peptide chain. Here we present a large-scale simulation study designed to examine the extent to which conformations of peptide fragments in water predict native conformations in proteins....

Descripción completa

Detalles Bibliográficos
Autores principales: Voelz, Vincent A., Shell, M. Scott, Dill, Ken A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629132/
https://www.ncbi.nlm.nih.gov/pubmed/19197352
http://dx.doi.org/10.1371/journal.pcbi.1000281