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Genetic Mechanisms in Apc-Mediated Mammary Tumorigenesis

Many components of Wnt/β-catenin signaling pathway also play critical roles in mammary tumor development, yet the role of the tumor suppressor gene APC (adenomatous polyposis coli) in breast oncongenesis is unclear. To better understand the role of Apc in mammary tumorigenesis, we introduced conditi...

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Detalles Bibliográficos
Autores principales: Kuraguchi, Mari, Ohene-Baah, Nana Yaw, Sonkin, Dmitriy, Bronson, Roderick Terry, Kucherlapati, Raju
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629572/
https://www.ncbi.nlm.nih.gov/pubmed/19197353
http://dx.doi.org/10.1371/journal.pgen.1000367