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Impact of age, leukocyte count and day 21-bone marrow response to chemotherapy on the long-term outcome of children with philadelphia chromosome-positive acute lymphoblastic leukemia in the pre-imatinib era: results of the FRALLE 93 study

BACKGROUND: We explored the heterogeneity of philadelphia chromosome-positive acute lymphoblastic leukemia (Ph1-ALL) in a study of the effect of early features on prognosis in children. Here we report the long-term results of the FRALLE 93 study conducted in the era before the use of tyrosine kinase...

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Detalles Bibliográficos
Autores principales: Gandemer, Virginie, Auclerc, Marie-Francoise, Perel, Yves, Vannier, Jean-Pierre, Le Gall, Edouard, Demeocq, Francois, Schmitt, Claudine, Piguet, Christophe, Stephan, Jean-Louis, Lejars, Odile, Debre, Marianne, Jonveaux, Philippe, Cayuela, Jean-Michel, Chevret, Sylvie, Leverger, Guy, Baruchel, Andre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629767/
https://www.ncbi.nlm.nih.gov/pubmed/19144139
http://dx.doi.org/10.1186/1471-2407-9-14