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Protein kinase R reveals an evolutionary model for defeating viral mimicry

Distinguishing self from non-self is a fundamental biological challenge. Many pathogens exploit the challenge of self discrimination by employing mimicry to subvert key cellular processes including the cell cycle, apoptosis, and cytoskeletal dynamics1-5. Other mimics interfere with immunity6, 7. Pox...

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Detalles Bibliográficos
Autores principales: Elde, Nels C., Child, Stephanie J., Geballe, Adam P., Malik, Harmit S.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629804/
https://www.ncbi.nlm.nih.gov/pubmed/19043403
http://dx.doi.org/10.1038/nature07529