Cargando…
Protein kinase R reveals an evolutionary model for defeating viral mimicry
Distinguishing self from non-self is a fundamental biological challenge. Many pathogens exploit the challenge of self discrimination by employing mimicry to subvert key cellular processes including the cell cycle, apoptosis, and cytoskeletal dynamics1-5. Other mimics interfere with immunity6, 7. Pox...
Autores principales: | Elde, Nels C., Child, Stephanie J., Geballe, Adam P., Malik, Harmit S. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629804/ https://www.ncbi.nlm.nih.gov/pubmed/19043403 http://dx.doi.org/10.1038/nature07529 |
Ejemplares similares
-
A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
por: Bayer, Avraham, et al.
Publicado: (2023) -
A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists
por: Carpentier, Kathryn S., et al.
Publicado: (2016) -
Antagonism of Protein Kinase R by Large DNA Viruses
por: Olson, Annabel T., et al.
Publicado: (2022) -
Rapid adaptation to human protein kinase R by a unique genomic rearrangement in rhesus cytomegalovirus
por: Child, Stephanie J., et al.
Publicado: (2021) -
Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins
por: Hollis, Jeremy A., et al.
Publicado: (2023)