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The gene coding for PGC-1α modifies age at onset in Huntington's Disease

Huntington's disease (HD) is one of the most common autosomal dominant inherited, neurodegenerative disorders. It is characterized by progressive motor, emotional and cognitive dysfunction. In addition metabolic abnormalities such as wasting and altered energy expenditure are increasingly recog...

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Detalles Bibliográficos
Autores principales: Weydt, Patrick, Soyal, Selma M, Gellera, Cinzia, DiDonato, Stefano, Weidinger, Claus, Oberkofler, Hannes, Landwehrmeyer, G Bernhard, Patsch, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630305/
https://www.ncbi.nlm.nih.gov/pubmed/19133136
http://dx.doi.org/10.1186/1750-1326-4-3