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Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway

BACKGROUND: Numerous proteins can be converted to amyloid-like fibrils to increase cytotoxicity and induce apoptosis, but the methods generally require a high concentration of protein, vigorous shaking, or fibril seed. As well, the detailed mechanism of the cytotoxic effects is not well characterize...

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Detalles Bibliográficos
Autores principales: Huang, Chun-Yung, Liang, Chi-Ming, Chu, Chiao-Li, Liang, Shu-Mei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630307/
https://www.ncbi.nlm.nih.gov/pubmed/19133118
http://dx.doi.org/10.1186/1472-6750-9-2