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Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway
BACKGROUND: Numerous proteins can be converted to amyloid-like fibrils to increase cytotoxicity and induce apoptosis, but the methods generally require a high concentration of protein, vigorous shaking, or fibril seed. As well, the detailed mechanism of the cytotoxic effects is not well characterize...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630307/ https://www.ncbi.nlm.nih.gov/pubmed/19133118 http://dx.doi.org/10.1186/1472-6750-9-2 |