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A rapid method for detection of five known mutations associated with aminoglycoside-induced deafness

BACKGROUND: South Africa has one of the highest incidences of multidrug-resistant tuberculosis (MDR-TB) in the world. Concomitantly, aminoglycosides are commonly used in this country as a treatment against MDR-TB. To date, at least five mutations are known to confer susceptibility to aminoglycoside-...

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Detalles Bibliográficos
Autores principales: Bardien, Soraya, Human, Hannique, Harris, Tashneem, Hefke, Gwynneth, Veikondis, Rene, Schaaf, H Simon, van der Merwe, Lize, Greinwald, John H, Fagan, Johan, de Jong, Greetje
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630920/
https://www.ncbi.nlm.nih.gov/pubmed/19144107
http://dx.doi.org/10.1186/1471-2350-10-2