Human Rad51 mediated DNA unwinding is facilitated by conditions that favour Rad51-dsDNA aggregation

BACKGROUND: Human Rad51 (RAD51), analogous to its bacterial homolog, RecA, binds and unwinds double stranded DNA (dsDNA) in the presence of certain nucleotide cofactors. ATP hydrolysis is not required for this process, because even ATP non hydrolysable analogs like AMP-PNP and ATPγS, support DNA unw...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Kamakshi, Krishnan, Neeraja M, Kulkarni, Anagha, Rao, Basuthkar J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630921/
https://www.ncbi.nlm.nih.gov/pubmed/19133161
http://dx.doi.org/10.1186/1471-2091-10-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630921/
https://www.ncbi.nlm.nih.gov/pubmed/19133161
http://dx.doi.org/10.1186/1471-2091-10-2

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