Cargando…
Human Rad51 mediated DNA unwinding is facilitated by conditions that favour Rad51-dsDNA aggregation
BACKGROUND: Human Rad51 (RAD51), analogous to its bacterial homolog, RecA, binds and unwinds double stranded DNA (dsDNA) in the presence of certain nucleotide cofactors. ATP hydrolysis is not required for this process, because even ATP non hydrolysable analogs like AMP-PNP and ATPγS, support DNA unw...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630921/ https://www.ncbi.nlm.nih.gov/pubmed/19133161 http://dx.doi.org/10.1186/1471-2091-10-2 |