Angiostatin anti-angiogenesis requires IL-12: The innate immune system as a key target

BACKGROUND: Angiostatin, an endogenous angiogenesis inhibitor, is a fragment of plasminogen. Its anti-angiogenic activity was discovered with functional assays in vivo, however, its direct action on endothelial cells is moderate and identification of definitive mechanisms of action has been elusive...

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Detalles Bibliográficos
Autores principales: Albini, Adriana, Brigati, Claudio, Ventura, Agostina, Lorusso, Girieca, Pinter, Marta, Morini, Monica, Mancino, Alessandra, Sica, Antonio, Noonan, Douglas M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630934/
https://www.ncbi.nlm.nih.gov/pubmed/19144161
http://dx.doi.org/10.1186/1479-5876-7-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630934/
https://www.ncbi.nlm.nih.gov/pubmed/19144161
http://dx.doi.org/10.1186/1479-5876-7-5

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