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Angiostatin anti-angiogenesis requires IL-12: The innate immune system as a key target
BACKGROUND: Angiostatin, an endogenous angiogenesis inhibitor, is a fragment of plasminogen. Its anti-angiogenic activity was discovered with functional assays in vivo, however, its direct action on endothelial cells is moderate and identification of definitive mechanisms of action has been elusive...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630934/ https://www.ncbi.nlm.nih.gov/pubmed/19144161 http://dx.doi.org/10.1186/1479-5876-7-5 |