Single-chain Fv phage display propensity exhibits strong positive correlation with overall expression levels

BACKGROUND: Single chain Fvs (scFvs) are widely applied in research, diagnostics and therapeutic settings. Display and selection from combinatorial libraries is the main route to their discovery and many factors influence the success of this process. They exhibit low thermodynamic stability, resulti...

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Detalles Bibliográficos
Autores principales: Scott, Nathan, Reynolds, Catherine B, Wright, Michael J, Qazi, Omar, Fairweather, Neil, Deonarain, Mahendra P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630973/
https://www.ncbi.nlm.nih.gov/pubmed/19113995
http://dx.doi.org/10.1186/1472-6750-8-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630973/
https://www.ncbi.nlm.nih.gov/pubmed/19113995
http://dx.doi.org/10.1186/1472-6750-8-97

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