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High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytes

BACKGROUND: Human B lymphocytes can produce leukotriene B(4 )but the biological function of the 5-lipoxygenase (5-LO) pathway in B cells is unclear. In order to better understand and define the role of 5-LO in B cells, we investigated the expression of 5-LO mRNA and protein in subsets of B cells fro...

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Detalles Bibliográficos
Autores principales: Mahshid, Yilmaz, Lisy, Marcus-René, Wang, Xiao, Spanbroek, Rainer, Flygare, Jenny, Christensson, Birger, Björkholm, Magnus, Sander, Birgitta, Habenicht, Andreas JR, Claesson, Hans-Erik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631017/
https://www.ncbi.nlm.nih.gov/pubmed/19134178
http://dx.doi.org/10.1186/1471-2172-10-2