Cargando…

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, Nrp1 null embryos display vascular defects that differ from those of mice lacking either VEGF-A164 or Sema3A proteins. Furthermore, it has been rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Valdembri, Donatella, Caswell, Patrick T, Anderson, Kurt I, Schwarz, Juliane P, König, Ireen, Astanina, Elena, Caccavari, Francesca, Norman, Jim C, Humphries, Martin J, Bussolino, Federico, Serini, Guido
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631072/
https://www.ncbi.nlm.nih.gov/pubmed/19175293
http://dx.doi.org/10.1371/journal.pbio.1000025