Structure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1.7 Å resolution

Disintegrins are a family of small (4–14 kDa) proteins that bind to another class of proteins, integrins. Therefore, as integrin inhibitors, they can be exploited as anticancer and antiplatelet agents. Acostatin, an αβ heterodimeric disintegrin, has been isolated from the venom of Southern copperhea...

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Detalles Bibliográficos
Autores principales: Moiseeva, Natalia, Bau, Robert, Swenson, Stephen D., Markland, Francis S., Choe, Jun-Yong, Liu, Zhi-Jie, Allaire, Marc
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631110/
https://www.ncbi.nlm.nih.gov/pubmed/18391413
http://dx.doi.org/10.1107/S0907444908002370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631110/
https://www.ncbi.nlm.nih.gov/pubmed/18391413
http://dx.doi.org/10.1107/S0907444908002370

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