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Differences in APOBEC3G Expression in CD4+ T Helper Lymphocyte Subtypes Modulate HIV-1 Infectivity

The cytidine deaminases APOBEC3G and APOBEC3F exert anti–HIV-1 activity that is countered by the HIV-1 vif protein. Based on potential transcription factor binding sites in their putative promoters, we hypothesized that expression of APOBEC3G and APOBEC3F would vary with T helper lymphocyte differen...

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Detalles Bibliográficos
Autores principales: Vetter, Michael L., Johnson, Megan E., Antons, Amanda K., Unutmaz, Derya, D'Aquila, Richard T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631133/
https://www.ncbi.nlm.nih.gov/pubmed/19197360
http://dx.doi.org/10.1371/journal.ppat.1000292