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Association of the Gene Polymorphisms IFN-γ +874, IL-13 −1055 and IL-4 −590 with Patterns of Reinfection with Schistosoma mansoni

BACKGROUND: The immunologic findings that most consistently correlate with resistance in human schistosomiasis are high levels of IgE and low levels of IgG4. We have genotyped gene and promoter polymorphisms of cytokines associated with regulation of these isotypes in a cohort of men occupationally...

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Detalles Bibliográficos
Autores principales: Gatlin, Michael R., Black, Carla L., Mwinzi, Pauline N., Secor, W. Evan, Karanja, Diana M., Colley, Daniel G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631135/
https://www.ncbi.nlm.nih.gov/pubmed/19190772
http://dx.doi.org/10.1371/journal.pntd.0000375