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Identification of Lympho-Epithelial Kazal-Type Inhibitor 2 in Human Skin as a Kallikrein-Related Peptidase 5-Specific Protease Inhibitor

Kallikreins-related peptidases (KLKs) are serine proteases and have been implicated in the desquamation process of the skin. Their activity is tightly controlled by epidermal protease inhibitors like the lympho-epithelial Kazal-type inhibitor (LEKTI). Defects of the LEKTI-encoding gene serine protea...

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Detalles Bibliográficos
Autores principales: Meyer-Hoffert, Ulf, Wu, Zhihong, Schröder, Jens-Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631147/
https://www.ncbi.nlm.nih.gov/pubmed/19190773
http://dx.doi.org/10.1371/journal.pone.0004372