Adverse effects of reduced oxygen tension on the proliferative capacity of rat kidney and insulin-secreting cell lines involve DNA damage and stress responses

Standard cell culture conditions do not reflect the physiological environment in terms of oxygen tension (20% vs 3%). The effects of lowering oxygen tension on cell proliferation in culture can be beneficial as well as detrimental depending on the cell line studied, but the molecular mechanism under...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Hua, Jones, R. Huw, Tarry-Adkins, Jane, Smith, Noel H., Ozanne, Susan E.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631166/
https://www.ncbi.nlm.nih.gov/pubmed/18692496
http://dx.doi.org/10.1016/j.yexcr.2008.07.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631166/
https://www.ncbi.nlm.nih.gov/pubmed/18692496
http://dx.doi.org/10.1016/j.yexcr.2008.07.017

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