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Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

BACKGROUND: Eukaryotic initiation factor 4E (eIF4E) is elevated in many cancers and is a prognostic indicator in breast cancer. Many pro-tumorigenic proteins are selectively translated via eIF4E, including c-Myc, cyclin D1, ornithine decarboxylase (ODC), vascular endothelial growth factor (VEGF) and...

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Detalles Bibliográficos
Autores principales: Kleiner, Heather E, Krishnan, Prasad, Tubbs, Jesse, Smith, Mark, Meschonat, Carol, Shi, Runhua, Lowery-Nordberg, Mary, Adegboyega, Patrick, Unger, Marcia, Cardelli, James, Chu, Quyen, Mathis, J Michael, Clifford, John, De Benedetti, Arrigo, Li, Benjamin DL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631459/
https://www.ncbi.nlm.nih.gov/pubmed/19134194
http://dx.doi.org/10.1186/1756-9966-28-5