Tumor necrosis is associated with increased alpha(v)beta(3 )integrin expression and poor prognosis in nodular cutaneous melanomas

BACKGROUND: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas of the vertical growth phase might lead to tissue hypoxia, alterations in apoptoti...

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Detalles Bibliográficos
Autores principales: Bachmann, Ingeborg M, Ladstein, Rita G, Straume, Oddbjørn, Naumov, George N, Akslen, Lars A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631589/
https://www.ncbi.nlm.nih.gov/pubmed/19061491
http://dx.doi.org/10.1186/1471-2407-8-362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631589/
https://www.ncbi.nlm.nih.gov/pubmed/19061491
http://dx.doi.org/10.1186/1471-2407-8-362

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