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Tumor necrosis is associated with increased alpha(v)beta(3 )integrin expression and poor prognosis in nodular cutaneous melanomas
BACKGROUND: Tumor necrosis and apoptotic activity are considered important in cancer progression, but these features have not been much studied in melanomas. Our hypothesis was that rapid growth in cutaneous melanomas of the vertical growth phase might lead to tissue hypoxia, alterations in apoptoti...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631589/ https://www.ncbi.nlm.nih.gov/pubmed/19061491 http://dx.doi.org/10.1186/1471-2407-8-362 |