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The effect of alternative permutation testing strategies on the performance of multifactor dimensionality reduction

BACKGROUND: Multifactor Dimensionality Reduction (MDR) is a novel method developed to detect gene-gene interactions in case-control association analysis by exhaustively searching multi-locus combinations. While the end-goal of analysis is hypothesis generation, significance testing is employed to in...

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Detalles Bibliográficos
Autor principal: Motsinger-Reif, Alison A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631601/
https://www.ncbi.nlm.nih.gov/pubmed/19116021
http://dx.doi.org/10.1186/1756-0500-1-139