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The effect of alternative permutation testing strategies on the performance of multifactor dimensionality reduction
BACKGROUND: Multifactor Dimensionality Reduction (MDR) is a novel method developed to detect gene-gene interactions in case-control association analysis by exhaustively searching multi-locus combinations. While the end-goal of analysis is hypothesis generation, significance testing is employed to in...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631601/ https://www.ncbi.nlm.nih.gov/pubmed/19116021 http://dx.doi.org/10.1186/1756-0500-1-139 |