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Retrovirus-Specificity of Regulatory T Cells Is Neither Present nor Required in Preventing Retrovirus-Induced Bone Marrow Immune Pathology

Chronic viral infections of the hematopoietic system are associated with bone marrow dysfunction, to which both virus-mediated and immune-mediated effects may contribute. Using unresolving noncytopathic Friend virus (FV) infection in mice, we showed that unregulated CD4(+) T cell response to FV caus...

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Detalles Bibliográficos
Autores principales: Antunes, Inês, Tolaini, Mauro, Kissenpfennig, Adrien, Iwashiro, Michihiro, Kuribayashi, Kagemasa, Malissen, Bernard, Hasenkrug, Kim, Kassiotis, George
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631611/
https://www.ncbi.nlm.nih.gov/pubmed/19006695
http://dx.doi.org/10.1016/j.immuni.2008.09.016